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Now, I'll preface my comments by saying this is not a situation I've mastered - I too am a beginner.
To discuss this hand, I think I would want to extend the scope of the discussion a bit to this: How can you profitably play 43s given the HH to this point and the villain profile?
The short answer is: "Just fold." In terms of hitting the flop and making a better hand than what he is likely holding - you are calling $2.5 to win approx $34 if and only if he's willing to stack off with what he has - which would give you odds of 17 to 1. If you had a pocket pair this would actually be slightly low odds to call for set value. One rule is that his stack needs to offer you odds of 20-25 to 1 even though you are about 8 to 1 to flop a set - because he simply doesn't stack off often enough. Check this one out:
http://www.flopturnriver.com/Common-Flop-Odds.html
Couple important ones:
I don't have the numbers for 43 as opposed to 54, but I know they are worse - but for the purposes of this discussion I'll use the numbers as if we were talking about 54.
As a basic calculation exercise you may want to consider why the correct way to arrive at flopping either a made straight, a made flush an open-ended straight draw or a flush draw is calculated in this way (for 54s): 1 - (1 - 0.00842 - 0.10944) * (1 - 0.01306 - 0.10449) / 100. Which is approximately 22.16%. This is a very rough order-of-magnitude calculation which probably counts a flopped straight flush twice - and it's worth keeping in mind that only around 2% of the time do you actually flop a completed flush or straight (and the villain could easily have a better flush) - by far the most of these flops that you 'hit' are still drawing hands and more likely to miss than hit on later streets.
To play this hand I think this is a situation where it's important to have an idea what the villain thinks. A lot of the value for you in this hand, if you play it, has to come from fold equity. That is, value that is realised by making him think you have a big hand and folding. If you do not think you can confidently play the hand in a way that translates into fold equity then you do need to fold (and fast).
To the above it is important what you think villain puts you on if you respectively call or re-raise pre-flop. If he puts you on something like 99-JJ if you call and the flop comes J73 rainbow can you play in a way that convinces him you have a set and he needs to fold his two overcards (which may be AK)? A pre-flop re-raise from you might fold out AK, AQ, JJ, TT or even QQ type hands - if he is one to 3bet them in the first place - and one to fold them if he does. He could call some of them.
With a 3.2 AF there's a risk you can't assume he'll let you see free cards - he might do re-raises and put you all-in if you bluff. If he doesn't get to fire the aggression he may be inclined to let a good hand go. It would be really useful if we had an idea of his 3bettting range. Being able to put more than AA or KK in his 3bet range would be great.
If...
.. you have a very good idea what the villain has
.. and this includes at least AK, but also preferably AQ and other unpaired overcards
.. you have a good tight image and know villain will put you on something like 99-JJ
.. villain can make big folds (AK/AQ at least on a missed flop - preferably also KK-QQ)
.. you plan to play any 9-J on the flop as if it's the mortal nuts
I can see a call here being a high variance slightly plus EV play - very occasionally. But you'd need to be mentally at peace with the idea that you might be putting your entire stack in on a bluff (if the conditions pan out). You can only realize the fold equity potential in this hand through aggression - and you can only play this hand profitably if you have fold equity.
If I the conditions were right and I decided to play this hand I would open push any flop with a 9-J on it, and maybe also any one-colour flop as he could have put AKs in your range also (and then hope he doesn't hold the A or K in the suit on the board). There are other lines you can take with other types of flops that convey the same image, but the question is if there are enough of them that you can play and play them convincingly and whether the villain can fold.
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