Seems like exploitation ought to be simple.

1) Figure out who the guy is that calls too much with weak holdings, Middle pair, top pair top kicker on a co-ordinated board. Wait until you have something really strong and bet all 3 streets.

2) Figure out the guy who folds too much and only ever shows down a straight and a flush, raise every pot he limps in, and bet, and bet, and bet again as long as the flush or straight doesn't complete. Charge him to enter the hand he wants to limp into, and autolead a large percentage of the pot when he checks to you.

3) Find that guy who only ever plays against 3-bets with AA, KK and AKs because he's 24 multitabling, and every time he raises, pop him back with any two cards. Walk away against any 4 bets, and play called 3 bets cautiously unless you are ahead of above said range post flop.

4) Find that Guy that floats every chance he gets. Let him float you when you have a nice hand, say top pair top kicker on a dry, or med dry board.

The list can go on for miles.

The reason why it's not so simple... is what I can't do, and that's: get the idiots who are playing predictably, to play predictably against ME!....