Quote Originally Posted by Fnord
They're the perfect NLHE hand because you're rarely going to be faced with a difficult decision with them.
If that means you should just set mine with them then I'm sure it's a losing play. If you're a really good post-flop player you might be able to play them but then you'll have to bluff sometimes and you'll have some difficult decisions after all in big pots out of position.

I stopped opening 22-66 UTG because I was down significantly over a large sample of hands.

I could limp with them, but this isn't 2004 anymore and people don't let you get away with it. If I'm at an all-star caliber table, sure I'll limp.