looking for some discussion opening ranges with limpers in 2 example situations...

do we adjust our opening ranges when we have limpers? or do 4x +1 with our entire opening range...

If I typically open with 22 in the cuttoff, what is the correct way to play it if UTG & UTG+1 both limped?
same situation, but I am in the BB...

also, whichever way we play this, what is our plan on a missed flop in both situations?

lets say this is 50NL 6-max