This hand hurt, obviously. So now I'm wondering if I ought to have seen some sort of sign here.
I'm just not sure how to distinguish what happened from TPTK or even overpair.

When do you stop putting them on overpair/top pair and start thinking 2pair/set? Is there actually an answer to this question?

** Fantastic Four [Hold 'em] (0.05|0.10 No Limit - Cash Game) Real Money
SB posted the small blind - $0.05
Anosmic posted the big blind - $0.10

** Dealing card to Anosmic: 3 of Spades, Queen of Diamonds

UTG folded
UTG+1 called - $0.10
3 fold
Villain called - $0.10
BTN folded
SB called - $0.10
Anosmic checked

** Dealing the flop: 8 of Hearts, Queen of Hearts, 3 of Diamonds

SB checked
Anosmic bet - $0.30
UTG+1 called - $0.30
Villain raised - $0.60
SB folded
Anosmic raised - $0.90
BTN called - $0.90
Villain raised - $1.20
Anosmic called - $1.20
BTN called - $1.20

** Dealing the turn: 7 of Diamonds
Anosmic checked
BTN checked
Villain went all-in - $4.77
Anosmic went all-in - $3.65
BTN folded

Villain shows: 8 of Spades, Queen of Spades
** Dealing the river: 10 of Clubs

Villain wins $11.00 from the main pot