Im new to the site here, so my opinion may not count for much. IMO playing outside of your comfort zone is a recipie for disaster. Considering that being uncomfortable at the level of the game will affect your desciscions in a very negative way... as in:
causing you through dicomfort to slow down for the wrong reasons in a hand
if you are not comfortable with the stakes you are playing your desciscions will not be motivated by a proper action according to the players and the state of the board.. but instead by your fears.