its hard to say without the whole play information from preflop to river. It all depends on how the flop was. If it there was already 2 suited on the flop and no one bet out big to chase away flush draws, then I would be more inclined to fold, however, if there was only 1 of your suit and you hit runner runner, then I might consider calling or even raising but then again it all depends on how your opponents have been playing up till now.