I think I'd have to agree that within the context of AD, Tobias and Buster are probably 1st and 2nd place. Thing is that I put Gob up there too.

Thing for me about AD characters is that they are all extremely good (except for Maebe and Michael's sister, who are just okay), but they all play very specific roles that compliment everything. Like Michael is the straight man around which the show plays, and because of this they're able to do wacky shit with the other characters. Curiously though, Michael, in all his straight man glory, actually spends a decent amount of time going out of that bound too. It's a very impressive dynamic, and I have no clue how they pulled it off

I mean the characters are so fucking good that they made an old spinster unloving cunt in Lucille fricken cool

If we're talking best comedy characters ever though I just may have to put Larry David in Curb above George. Same character, I guess, but if I had to choose which one is better I'm not sure. Charlie and Dennis from Philly and Randy Marsh from South Park are other contenders off the top of my head