SUPERAntiSpyware is an excellent program. Like Malwarebytes' Anti-Malware, it comes in a free, as well as paid, version. Real-time protection is only available in the paid version. It is an excellent on-demand scanner in the free mode.

It will detect Spyware, Adware and Malware (Trojans, Dialers, Worms, KeyLoggers, HiJackers, Parasites, Rootkits, Rogue Security Products) and many other types of threats.

Pretty much everything it detects, you do not want on your computer. It will not see Holdem Manager as a "bad" program, but if HM has infected files, they will be flagged for cleaning/deleting. If you are concerned, you could look at everything one-by-one. But, again, if it is flagged, there is a problem.