Taxi, Nice odds on Boston! To answer your question the bet IS void if those pitchers don't start. I prefer to go with the bet only if the noted starters actually start (which they do about 95% of the time anyway) as that is one of the key factors in how the oddsmakers determine their lines. Others are a) which team is at home; b) overall team ability. The reason that Boston is the underdog tonight is because they are playing against a quality pitcher on the road.