What's a good sample size for reads?

Yesterday I made the permanent move to 5NL with 15 buyins (willing to drop down at ~13 BI). I grinded it for a while and was up about a buyin with a pretty cold wave of cards. Finally on one of my tables i got KK utg and went ahead and did the standard 4x.

The button, who was 12/1/.9 over 150 hands, re raises about 2.5x my original raise. With only a 1% PFR i was pretty sure he had aces, but since i was only 100 BB deep i went ahead and came over the top of him and we got it all in preflop. Sure enough, he had AA

Since in my case i was only 100 BB deep I feel the shove was standard. What if i was 200+ BB deep though? Is there any sample size which gives a fairly reliable read to lay down KK against the nittiest of nits?

Do you mean reads where you kinda of understand their approach to the game? Or reads as in, Hold'em Manager plz tell me what to think via your almighty HUD?

Standard fold imo.