I don't think the benefit here comes from pot odds.. your stack being so much bigger than his doesn't really affect those odds. The smaller of both the stacks is kinda the 'upper limit' of the show-down.

The advantage is probably more a psychological one. Small is more likely to do desperation bets, more likely to fold when pressured by a big stack opp (cuz of intimidation), and more likely to generally suck at poker.

But all in all I'm still struggling to grasp these odds fully myself. Take for example this situation: you have put $5 in the pot, and so has your opp. So the pot is $10. Your opp goes all-in for $10. You have a flush draw. Should you chase?

* if you calculate pot odds, you have 37% to hit the flush, and need to invest 33% so it's a good idea
* if you calculate the total however, you have 37% to hit the flush, and you will have invested $15 in a $30 pot, so 50%. So this is not in your favor.

Which interpretation to take?