This is a topic I've been wanting to talk about because I've noticed a LOT of players seem to HATE playing against shortstackers. While I wouldn't say I LOVE shortstackers, I think I've noticed to this point ($50NL starting from $2NL), I have been and have continued to make a LOT of money from them. I certainly don't avoid them and compared to nitty regulars, I prefer shortstackers because they seem like easier, looser targets.

For starters, shortstackers, by and large, are bad players. They don't want to play post flop. Many times, for whatever reason, they are simply scared to play with more money. They don't have any imagination. They either push or fold pre-flop or try to get in cheap pre-flop and then push or fold on the flop. To answer your question, there is no one size fits all approach. You need to take notes, get reads, establish ranges, figure out your equity, and make a decision that is the most EV for you. Some shortstackers may only push with ACES or KINGS and you'll never want to play back unless you have ACES. Some may push with any pocket pair and you'll do well to call with 9's or better. It's just a matter of figuring out what kind of short stacker they are and exploiting it. It's so easy to put pressure on them post flop because they will frequently tell you if they have it or not after one cbet or donk bet. Bombs away on a scary all flushed or paired board. They have no wiggle room to wait for more cards, value bet, or bluff. They are at a big disadvantage and I would NEVER recommend anyone play poker using a short stacking strategy.

Good luck.