Your flop bet makes it looks like you are betting middle pair or somesuch. I'd probably call there and hope someone else in the hand does as well to help finance. I fold the turn...your bet there is fine, and of course you have pot odds to call the river, though it's fairly obvious when he comes out firing what hand he has.
So, bet 150 - 200 on the flop, continue on the turn 3/4 pot, check river, or stop and think a bit before calling anything unreasonable that he fires off.