Overpairs in Multiway Pots

How much more careful do you guys play with your overpairs when you get involved multiway? It seems like when you get 2 callers pre-flop and on the flop that you are about doomed to lose your stack (should they have a 2pair/set) if you bet the normal 4-6BB's pre-flop & 2/3-PSB on the flop. How do you usually react on the turn once you've built a ~50BB pot vs. 2 opponents assuming no obvious draws have completed?

... it depends.

What is my position?
Are opps reasonable or nincompoops?
How strong is my overpair? Was I the preflop aggressor?

Typically I will play out my overpair with the working assumption that it's the best hand until betting shows me otherwise. Note that this doesn't mean that I go crazy either...

I also tend to raise a fair number of hands prelfop (~ 10%) and tend to cbet them as well. This probably affects the way I play overpairs and how I'm perceived on the table.

Originally Posted by Blinky

... it depends.

What is my position? how about give your answer for different positions?
Are opps reasonable or nincompoops? reasonable
How strong is my overpair? AA/KK
Was I the preflop aggressor? yes

If you get to the turn with a ~50BB pot vs. 2 opponents and you are OOP betting strong then a push from a full stack (which would be the classic monster line) won't even be a minraise. Against 2 opponents I feel pretty suspicious with both calling my flop cbet, and I'm wondering how others approach the situation.