as for OP, there is never going to be a one-size-fits-all answer. learning to spot profitable set-mines is something you'll have to do for/by yourself in your own time. it's basically learning to figure out whether you will win enough the times you hit to at least cover the amount you lose the times you are forced to C/F. villain's tendencies are vital here. is their 3b range strong enough for you to get paid? or is he bluffing some decent frequency and thus we wont get paid frequently? what is his postflop game like? is he the kind of villain who will ALWAYS make you C/F when you hit (probably indicated by high flop CB)? does he have any spewy postflop tendencies which mean you will get paid off often even when he has medium or mediocre holdings? etc etc. for help with the maths side of it, search the forum for "about implied odds" and find spoon's post.
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