Logic is a system of principles of reasoning. In this case, if your call is not profitable, you don't make it. You use math to come to this logical conclusion.

As for the variable, I mean factoring in the percentage chance it's a bluff. If he's bluffing you have him beat for sure, so you can add that to his range. If he's bluffing 80% of the time he makes a huge bet, our odds are massively improved, if its more like 5-10% chance, then our odds are reduced.

If you're not a fan of variance, you'll fold it. That's not really listening to logic though, if you ask me. Logically speaking if the call is EV+ you make it I think.