With a lot of callers I'm playing a lot of hands out of the SB.. generally calling anything with potential (any suited, any connected, low-mid PP, high cards) and raising my huge hands (usually QQ-AA). If the open-limper is weak and I'm confident the others just followed in because of increasingly better pot odds, I'll throw in a > pot sized raise with any 2, but that's a move I use sparingly.