To answer the question posed in your subject: No, it is not possible to play against too many fish. The more the better. Like it was already said, you have to adjust your game.

I think the key is playing the player, not adjusting to the "table." Fortune 500 hit it right on. You have to loosen your starting standards because if you wait around for great starting hands, you will have waited in vain because you will be up against 3 players, one of whom will probably out draw you.

How to play against fish is an extremely common question on here, so I wrote up this guide a while back that has been virtually ignored due to its simplistic subject matter.

http://www.flopturnriver.com/phpBB2/...pic.php?t=7282