Player A is better than Player B + Player A has position on Player B + Player A has a better hand than Player B = Player A will get the best of it.

If both players are weak, I would assume Player A would get the best of it because of hand + position.

If both players are strong, I would assume the same as two weak players.

If Player B is stronger than Player A, I would assume Player B would get the best of it if played correctly ie. check/fold mode + maximizing set profits.