How do you know?

How do you know when your opponents just do not have a hand to call you with? Or you are simply not scaling your bets correctly?

Table image for myself is: Tight/Aggressive

Here is a hand: 0.10/0.25NL

SB ($10.68)
BB ($21.01)
UTG ($15.88)
UTG+1 ($25.00)
Hero ($14.05)
UTG+3 ($28.27)
HJ ($28.14)
CO ($20.59)
D ($9.92)

Hero was dealt Ah/Ad

Preflop:
Small Blinds $0.10
Big Blinds $0.25
UTG folds
UTG+1 raises $0.75
Hero calls $0.75
UTG+3 folds
CO calls $0.75
D calls $0.75
SB folds
BB folds

Flop($3.35) -- Kd/2s/6s
UTG+1 checks
Hero bets $2.00
CO folds
D folds
UTG+1 folds

Hero wins Pot.

There are other similar hands to this one, where other players call C-Bet and then folds turn Or folds after my C-Bet. My C-Bets are generally 60-70% of pot size, is that the correct amount?

I've noticed that my sessions are distorted with an asymmetric payoff, where winning pots are much lower than losing pots on an absolute basis. For instance, my last session, I lost an all-in pot with QQ VS AK off (All in preflop & the guy rivered an ace).

Thanks for the help.