Reads are important when determining if you are up against a set. When the "tables are turned" I'm suspicous of a set, but not paranoid enough to lay down my hand in both examples you give without an extremely strong read. I think a better example would be:
You have KK and the flop is 59T and you meet major resistance from somebody who limp/called preflop.

9bb/100 is good by the way.