I'm not a big fan of overbetting the pot without very good reason to do so. Even if there are draws on the board, just give drawers poor drawing odds and force them to make a mistake by calling or raising. Even if they hit, there is still potential to win a monster pot by filling up.
Good point. Simply put, there's two schools of thought wrt draws: 1) overbet pot; 2) give poor drawing/pot odds. Both have advantages and disadvantages. With (2), you must be willing to lay down your hand if you encounter huge resistance and the apparent draw is filled. With a flush draw this is fairly obvious, but its not so obvious with straight draws. Also, you have to factor in bluffing. The big advantage is that you can get big money by doing this. For example, say you have a hit set on a two suited flop. You have op on a flush draw, so you bet the pot on the flop. Op turns a flush and bets. You still have 10 outs to the boat or better so you call and river a boat/4 of a kind (assuming he didn't bet too big to negate pot/implied odds). In all likelihood you'll stack your op. This can also happen simulataneously (ie. card giving 3 suited board also pairs the board) which is the ideal situation.

With (1), you'll push out people who will chase with bad odds, losing profit there, yet people who will push AI on a draw will still destack you every 1 in 3 times. This *may* decrease EV I guess, though I'm not really convinced. However, this is less complicated than (2) and for the most part ensures your money is in the middle with the best hand.