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You are oversimplifying things I think. Its not all about which hand has better odds to win. Thats only part of it.
 Originally Posted by jackvance
when you're holding AK or AQ or something, you HAVE TO bet big at preflop to weed out the lower pocket pairs.. because if it comes to a face-off it's a cointoss, and you stand to gain little and risk to lose a lot because of the nature of the cards.
Raising preflop with AK doesn't weed out lower PP's. It only weeds out trash hands like Q8s. Pairs still call to play for their set. The only reason you raise with AK is to weed out trash hands and to establish control of the hand. In fact, if there are any pocket pairs out there when you raise (which there usually is), you are raising with AK as a slight underdog, and you don't really care about that.
 Originally Posted by jackvance
But from the side of the pocket pair.. facing a big preflop raise.. this could also mean he has you dominated very easily.. so it's not very profitable to call this, unless you want to take the risk.. and if it comes to a showdown, you better pray he has unpaired cards.
When call a preflop raise with a small pair, it is irrelevant whether or not you are dominated. In fact, you hope the raiser has you dominated with AA or QQ or something.
 Originally Posted by jackvance
and after that calculate pot odds for your set, which are abysmal so probably best to fold out unless the other guy lets you have a look for free.
You can and should call raises outside your 8:1 pot odds requirement with small pairs. The reason for this is because you aren't playing for the money in the pot, you are playing for the opponents whole stack, which you will be taking most of the time if you hit your set and he has an overpair to the board. This is called implied odds. Do a forum search to learn more.
Also, another thing to think about is all the dead money in the pot. Say you have a big stack and AK. A medium-short stack goes all in after a bunch of limpers with what you suspect to be a small pair. Sure you are a slight underdog to win this, but keep in mind all of the limpers' money in the pot. If you reraise to isolate, all that dead money is free to take, and it makes your call very profitable.
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