Does anyone ever bluff raise IP over river bets that appear to be a medium/marginal hand betting for value?

I was reading a hand in the SH forum and someone was explaining why they would make a bigger bet on the river than one for value. Besides the fact that it maximized value due to villans calling tendencies in his short history, a big bet also reduced the chance that villan would bluff raise Hero off of his hand. It got me thinking about how to exploit value bets opponents make on the river. What textures/opponents are you looking for if you were going to be bluff raising a value bet?