Alright. It comes down to reads. If the guy is aggressive every time he preflop raises, you've got the best of it. If he's tight/weak, you're probably outkicked or staring down Queens full.
If you put in a re-raise and get pushed, not many hands are going over top of you and losing (especially since they raised preflop.) I think with deep stacks, a reraise/fold line would be best.
-'rilla