shorthanded game is definitly different from full table game.

my 2 cents

1. You have to be involved in more hands, otherwise the blinds will eat you alive. I think about 25% of the hands is a reasonable number.

2. Most pots are 2 or 3 way, so you want to avoid playing hands like low-mid suited connectors and probably low pocket pairs in a riase pot.

3. Hands like AQ, AJ, AT, KQ go up in value

4. You have more oppurtinities to bluff - use them.

5. Other people have more oppurtinites to bluff - get good reads on them and destack them when they do.