There are quite a few considerations. It depends on the position of the limpers and their style of play, your position and your hand. If you see a guy playing KT and A8 from OOP and he limps into a pot, he will get less respect from me than a guy who's only showed AK or better.

In general you don't want limpers in your pot when you are playing strong high-cards... but, you DO want limpers in the pot when you are playing for a set or suited connectors.

In the former case, you are looking to make TP types of hands and you are vulnerable to 2pr and drawing hands. In the latter case you are trying to flop a monster hand which you can slow-play to draw money into a huge pot.