I've been in similar situations so here is my general outlook...
My strategy is generally to identify when people have big hands and who is giving away their money. I'll go out of my way to call pairs and suited aces and suited connected cards with these players. Position helps. I still play tight in Early position and I just build a pot with hands that have the potential to stack players.

I do limp alot of AJo/ KQo type hands in EP because I feel they have less value in super deep stack situations. Its all about those few times you hit a nut hand/2 pair/trips/straight and stack someone who is overplaying their hand.

I find in these games that I can easily lose a couple hundred just trying to hit flops, but when you do hit a big one in comes in even faster.

Here is an example: Eff stack = $600
Crazy loose whale w/ 20k in his pocket raises to $25, passive gambler calls, I'm sitting on the button with T9s and this is an easy call IMO.
Flop is 678 rainbow... and I get both guys to stack off to me. One guy has 45 and the whale had J5o....LOL.

I'm not sure about throwing away the unsuited broadway hands...because if you hit 2 pair they probably won't get away from TPTK and you can win a huge pot. I would probably call a raise up to 15$ but I wouldnt call a 25$ raise.