I'd deem the "hand combinations" idea as one factor of many when creating a read.

e.g.
"Hmmm... He reraised preflop, and he's pretty solid, so AK and AA both make sense given the action of the hand. I'd normally lean towards villain having AA in this spot given the reraise but since that hand has a lower probability of being dealt out I'll decide it's 50/50 either way."

I would then proceed to felt it; Villain flips over his hand.

77.