Position doesn't matter post flop when deciding whether to call a preflop raise. It is your position preflop that matters. I will call a sizeable raise with low pairs if I know there will be no more raises behind me. For example if I am in the BB and UTG raises 6xBB, I will call if it is not raised again, unless it's folded around to me, then I have to make a judgement about the raiser, mainly whether he'll stick to his premium hand and pay me off all the way if I hit or whether he'll fold. If there are any callers I'm in there for sure.

Conversely, if I'm two off the button I will not call a sizeable raise, or even a decent raise, for fear of getting shut out of the pot by the people who have yet to act.

Once you get to the flop, it's flop or drop. Unless you get a pretty good flop like 345 rainbow to your 66.